Tuesday, January 31, 2012

Marijuana Mouth Spray: Will Cancer Pain Reliever Be Abused?

Image: GW Pharmaceuticals

The medical marijuana drug Sativex, which could be approved in the United States in the coming years as a treatment for pain relief, has little potential for abuse, experts say.

The British pharmaceutical company GW Pharmaceuticals is currently testing the drug, which is delivered as a mouth spray and called Sativex, in clinical trials. The company plans to seek U.S. Food and Drug Administration approval for the drug as a treatment for cancer pain when the trials are completed, likely sometime in 2014, a spokesperson for GW Pharmaceuticals told MyHealthNewsDaily.

The active ingredients in Sativex, known as cannabinoids, are derived from the cannabis plant. It is the first marijuana-based drug to be made by extracting the compounds from the plant, rather than synthesizing them. Two other drugs, Marinol and Cesamet, based on synthetic cannabinoids, were approved by the FDA in the 1980s.

Because the drug contains THC, the ingredient primarily responsible for marijuana's "high," it's possible people would use the drug for recreational rather than medical purposes.

"There is no doubt in my mind that there will be people that abuse it," said Dr. Jeffrey Bernstein, director of the Florida Poison Information Center at the University of Miami Miller School of Medicine.

However, because the drug is delivered through ingestion, rather than smoking, it would take much longer to have an effect ? at least an hour, compared with the minutes it takes to get high after smoking marijuana, said Margaret Haney, a professor of clinical neurobiology at Columbia University. This means drug users seeking a high would be less likely to abuse it. "Smoking is a really effective way to get a chemical into the brain," Haney said. The mouth spray "is a far safer administration,"she said.

And Marinol and Cesamet, which are also administered orally, have a low rate of abuse. "We don?t see a lot of problems from [those]," Bernstein said.

Not the same high
GW Pharmaceuticals intends to market Sativex in the United States for treatment of cancer pain. The drug is already approved in United Kingdom, Spain, Canada and New Zealand to treat muscle spasms due to multiple sclerosis, according to the company website.

Patients can adjust the dose of Sativex to prevent it from entering the blood too rapidly, allowing them to experience symptom relief without the marijuana high, according to GW Pharmaceuticals.

In addition, while marijuana is a hodgepodge of about 64 different substances, Sativex is composed mainly of two ingredients: THC and another cannabinoid called CBD. The latter component is thought to ameliorate some of the side effects of THC, including the high that marijuana users feel, said Dr. Armando Villarreal, an assistant professor of neurosurgery and pain management at the University of Rochester Medical Center in New York.

And for habitual marijuana users, the cultural and ritualistic practices that go along with smoking pot, such as passing a joint, may be an important part of the experience, Bernstein said. These rituals cannot be replicated with the spray. "A lot of people that smoke marijuana would rather smoke it," he said.

Unlikely overdose
Unlike drugs such as painkillers, which come with a risk of death if people take too much, patients who "overdose" on the marijuana spray would be at little risk for acute health problems, Haney said.

"What could happen is the person could get very uncomfortably intoxicated," Haney said. But in terms of other serious health effects, "there's none that I know of," Haney said.

Source: http://rss.sciam.com/click.phdo?i=3269dd8b17fc328b232cdbd47c6ad28f

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Fama on Finance | EconTalk | Library of Economics and Liberty

Eugene Fama of the University of Chicago talks with EconTalk host Russ Roberts about the evolution of finance, the efficient market hypothesis, the current crisis, the economics of stimulus, and the role of empirical work in finance and economics.

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0:36Intro. [Recording date: January 17, 2012.] Russ: Your impact on the field of finance has been immense--in a whole bunch of areas, but one that stands out is the efficient markets hypothesis (EMH). I'd like you to sketch out the evolution of that idea in the field, how it was understood initially, and how it has changed over time. Guest: How much time do we have? Russ: Well, four or five hours, but let's try to keep it to under 10 minutes for this first question, if you can. Guest: Okay. I'll go back to the beginning. The way Harry Roberts tells it, Holbrook Working in the 1930s started to become interested in whether speculative prices moved randomly. He was mostly an agricultural economist, looking at agricultural commodities, and he took a series of random numbers, simulated them, and brought them to his faculty at Stanford, faculty lounge, I guess; showed them to them and they agreed they were an agricultural series. So he thought from that that maybe a random walk kind of model would work pretty well for agricultural prices, prices of other commodities. But then there was a big gap from there to like the end of the 1950s. And what opened things up was the coming of computers, which made computations much easier. And the most readily available data was stock price data. So, basically, statisticians, econometricians took the data and started doing calculations on it, calculating autocorrelations with their estimates of how predictable returns are based on past returns. And then they stopped. Economists got into the mix and said: Okay, how would we expect prices to behave if they were set based on all available information? Which is basically the EMH, but it wasn't stated in those terms at that time. So, they said: I think they should be a random walk, an hypothesis pulled out of the air. Russ: When you say it's a random walk, explain what that means. Guest: That means that expected changes are successive changes are independent of one another. It also means they have identical distributions, but that part is not important. It's basically the independence part that's important. It basically means that you can't predict future returns based on past returns. Russ: And yesterday doesn't tell you anything about tomorrow. Guest: Right. Returns from day to day are basically independent of past returns. Now that was a very extreme hypothesis. Let me give you an example. You wouldn't say that about tomatoes, for example. Tomatoes are going to be cheaper in August than in January, for the most part, because they are seasonal. It has to do with supply and demand--mostly supply of tomatoes. There's a similar thing operating in prices of stocks, bonds, whatever. Basically, there's an expected return component, what people would require in order to hold those securities; and there's no reason that that has to be independent through time. There's no reason why that's not predictable or why it doesn't go--and there's lots of evidence that it is--higher on stocks during recessions and lower during good times. So there can be predictability in returns that is consistency with efficient markets. What people didn't understand in the beginning was that propositions about how prices should behave had to be joined to a statement about how you think they ought to behave. In other words, what you need is some statement about what we call a market equilibrium. What is the risk-return model you have in mind underlying the behavior of the prices in returns? So, for example, stocks are very risky; they require a higher expected return than bonds; and you have to take that into account in the tests. So there is this, what I call the joint hypothesis problem, which is basically what I added to the mix, but it's kind of an important part of it. It says whenever you are testing market efficiency you are jointly testing efficiency with some story about risk and return. And the two are joined at the hip. You can't separate them. So, people infer from that, it means market efficiency is not testable on its own. And that's true. But the reverse is also true. A risk-return model is untestable without market efficiency. Most risk-return models assume that markets are efficient. With very few exceptions.
6:18Russ: And so when we say markets are efficient, what do you mean by that? Guest: What you mean is that prices at any point in time reflect all available information. Russ: Now that idea--what's the distinction between the weak form and the strong form that people talk about? Guest: Two words that I used in 1970 that I came to regret. Because I was trying to categorize various tests that were done. So, I called weak form tests, tests that only used past prices and returns to predict future prices and returns. And I called semi-strong form tests, tests that used other kinds of public information to predict returns, like an earnings announcement or something like that. And then I called strong form tests, tests that look at all available information; and those are basically tests of if you look at groups of investment managers and you look at returns that they generate, you are basically looking at all the information they had to generate to [?] securities, and what's the evidence that the information they had wasn't in prices. Russ: And empirically, where do we stand today, do you believe and what has been established about those various hypotheses? Guest: Well, believe it or not, the weak form one has been the one that has been subject to the most, what people call anomalies, in finance. Things that are inconsistent with either market efficiency or some model of risk and return. The big one at the moment is what people call momentum--prices seem to move in the same direction for short periods of time. So, the winners of last year tend to be winners for a few more months, and the losers tend to be losers for a few more months. In the strong form tests, Ken French and I just published a paper called "Luck Versus Skill in Mutual Fund Performance," and basically looked at performance of the whole mutual fund industry--in the aggregate, together, and fund by fund, and try to distinguish to what extent returns are due to luck versus skill. And the evidence basically says the tests it's skill in the extreme. But you've got skill in both extremes. That's something people have trouble accepting. But it comes down to a simple proposition, which is that active management in trying to pick stocks has to be a zero sum game, because the winners have to win at the expense of losers. And that's kind of a difficult concept. But it shows up when you look at the cross section of mutual fund returns, in other words the returns for all funds over very long periods of time. What you find is, if you give them back all their costs, there are people in the left tail that look too extreme and there are people in the right tail that look too extreme, and the right tail and left tail basically offset each other. If you look at the industry as a whole; the industry basically holds a market portfolio. That's all before costs. If you look at returns to investors then there is no evidence that anybody surely has information sufficient to cover their costs.
10:11Russ: Which says that for any individual investing, certainly someone like me, that is, who doesn't spend any time or very much time at all looking--in my case no time, but let's suppose even a little time--trying to look at what would be a good investment. The implication is to go with index mutual funds because actively managed funds can't outperform. Guest: Well, no, it's more subtle than that. What's more subtle about it is, even if you spent time, you are unlikely to be able to pick the funds that will be successful because so much of what happens is due to chance. Russ: So, for me the lesson is: buy index mutual funds because the transaction costs of those are the smallest, and since very few actively managed funds can generate returns with any expectation other than chance to overcome those higher costs, I can make more money with an index fund. Guest: Right. Now, it's very counterintuitive, because we look at the whole history of every fund's returns, and sort them, and really the ones in the right tail are really extreme. Russ: Some great ones. Guest: They beat their benchmarks by 3-6% a year. Nevertheless, only 3% of them do about as well as you would expect by chance. Now what's subtle there is that by chance, with 3000-plus funds, you expect lots of them to do extremely well over their whole lifetime. So, these are the people that books get written about. Russ: Because they look smart. Guest: What this basically says is that there is a pretty good chance they are just lucky. And they had sustained periods of luck--which you expect in a big sample of funds. Russ: Of course, they don't see it that way. Guest: No, of course not. Russ: A friend of mine who is a hedge fund manager--before I made this call I asked him what he would ask you, and he said, well, his assessment is that efficient markets explain some tiny proportion of volatility of stock prices but there's still plenty of opportunity for a person to make money before markets adjust. And of course in doing so, make that adjustment actually happen and bring markets to equilibrium. Somebody has to provide the information or act on the information that is at least public and maybe only semi-public. What's your reaction to that comment? Guest: That's the standard comment from an active manager. It's not true. Merton Miller always liked to emphasize that you could have full adjustment to information without trading. If all the information were available at very low cost, prices could adjust without any trading taking place. Just bid-ask prices. So, it's not true that somebody has to do it. But the issue is--this goes back to a famous paper by Grossman and Stiglitz--the issue really is what is the cost of the information? And I have a very simple model in mind. In my mind, information is available, available at very low cost, then the cost function gets very steep. Basically goes off to infinity very quickly. Russ: And therefore? Guest: And therefore prices are very efficient because the information that's available is costless. Russ: But what's the implication of that steep incline? That information is not very-- Guest: It doesn't pay to try to take advantage of additional information. Russ: It's not very valuable. Guest: No, it's very valuable. If you were able to perfectly predict the future, of course that would be very valuable. But you can't. It becomes infinitely costly to do that. Russ: So, your assessment, that you just gave me of the state of our knowledge of this area, I would say remains what it's been for some time--that at the individual certainly there is no return to--prices reflect all publicly available information for practical purposes for an individual investor. Guest: For an individual investor? Even for an institutional investor. Russ: Correct. So, what proportion of the economics and finance areas do you think agree with that? Guest: Finance has developed quite a lot in the last 50 years that I've been in it. I would say the people who do asset pricing--portfolio theory, risk and return--those people think markets are pretty efficient. If you go to people in other areas who are not so familiar with the evidence in asset pricing, well, then there is more skepticism. I attribute that to the fact that finance, like other areas of economics, have become more specialized. And people just can't know all the stuff that's available. Russ: Sure. Guest: There's an incredible demand for market inefficiency. The whole investment management business is based on the idea that the market is not efficient. I say to my students when they take my course: If you really believe what I say and go out and recruit and tell people you think markets are efficient, you'll never get a job. Russ: Yes, it's true. And so there's a certain bias, you are saying, to how people assess the evidence. Guest: There's a bias. The bias is based, among professional money managers, the bias comes from the fact that they make more money from portraying themselves as active managers. Russ: That's true in macroeconomics as well. We'll get to that a little later in the conversation.
16:50Russ: I was going to ask you about the current crisis. Guest: I have some unusual views on that, too. Russ: I'd say that the mainstream view--and I recently saw a survey that said--it was an esteemed panel of economists; you weren't on it but it was still esteemed, both in finance and out of finance. And they asked them whether prices reflected information and there was near unanimity. Some strongly agreed; some just agreed. But there was also near unanimity that the housing market had been a bubble. Guest: The nasty b-word. Russ: Yes; and was showing some form of what we might call irrationality. Guest: Okay, so they had strong feelings about that, getting mad about the word bubble. Russ: Why? Guest: Because I think people see bubbles with 20-20 hindsight. The term has lost its meaning. It used to mean something that had a more or less predictable ending. Now people use it to mean a big swing in prices, that after the fact is wrong. But all prices changes after the fact are wrong. Because new information comes out that makes what people thought two minutes ago wrong two minutes later. Housing bubble--if you think there was a housing bubble, there might have been; if you had predicted it, that would be fine; but the reality is, all markets did the same thing at the same time. So you have to really face that fact that if you think it was a housing bubble, it was a stock price bubble, it was a corporate bond bubble, it was a commodities bubble. Are economists really willing to live with a world where there are bubbles in everything at the same time? Russ: And your explanation then of that phenomenon? Guest: My explanation is you had a big recession. I think you can explain almost everything just by saying you had a big recession. A really big recession. Russ: And why do you think we had a really big recession? Guest: I've heard some of your podcasts; I'm with you. I don't think macroeconomists have ever been good at knowing why we have recessions. We still don't understand the Great Depression. Russ: True. Although Ben Bernanke would argue, and Milton Friedman would argue and he did before he passed away, that monetary policy is a huge part of it. Guest: Let me reflect. I had this discussion with Milton, actually; and what I pointed out was from your own data, they show that there were massive free reserves throughout the Great Depression. And my point is: we can't force people to move demand deposits. Or to make love to anyone. Russ: Well, you can but it's not very productive. Guest: It's not very productive. M1 and M2--those things are basically endogenous. Russ: I have the same feeling. Guest: The only thing that's sort of exogenous is the monetary base. Russ: What did Milton say to that? Guest: All I gathered from Milton was: Interesting. Even when you won you thought you lost. Russ: Yes, I know. I had plenty of those. So, are you saying that that's analogous to our current situation? Guest: Oh, no. What I'm saying is that for example people want to blame the recession on the housing sector crashing and subprime mortgages. But if you are an economist and you are thinking about that, you have to be saying that there was some misallocation across markets, that margins weren't being equated across markets. That's pretty hard to accept because people are acting in all markets, working in all markets. That's a pretty tough one to follow. Russ: Well, a lot of people swallow it. Here's their version. They say things like there are these things called animal spirits that you can't measure, but that doesn't mean they are not real; that people get all excited about a particular asset class--in this case it was housing. And as those prices start to rise it becomes rational to speculate that it will continue to rise. And as that happens--as you would admit, people are making money along the way--and then they don't. They stop making money; the prices collapse. And this happens from time to time because of irrational exuberance; and that's just an aspect of capitalism. That's the standard counterpoint. Guest: Okay, but it wasn't just housing. That was my point when we started. The same thing was going on in all asset markets. Russ: Well, the timing isn't quite identical for all asset markets, right? The stock market--the housing market starts to collapse I think around early-mid-2006. Guest: It stops rising, right. Russ: And then begins a steady decline. Guest: That decline was nothing compared to the stock market decline. Russ: But when did that happen? Guest: I don't know the exact timing. Russ: It's not around then. It's later. Guest: The onset of the recession started with the collapse of the stock market. The recession and the collapse of the stock market, the corporate bond market, all of that basically coincides. But that also coincides with the collapse of the securitized bond market. Russ: Mortgage-backed securities. Guest: The subprime mortgages and all of that. Russ: Well, yes; that happens through 2007, 2008. I guess there is some parallel. So, you are going to reverse the causation. Guest: I'm not saying I know. What I'm saying is I can tell the whole story just based on the recession. And I don't think you can come up with evidence that contradicts that. But I'm not saying I know I'm right. I don't know. I'm just saying people read the evidence through a narrow lens. Russ: Yes, they do. Confirmation bias. Guest: And the rhetoric acquires a life of its own; so there are books written that basically all say the same thing about the crisis. Russ: And you are arguing that they have essentially cherry-picked the data. Guest: Well, they just look at pieces of the data and the fact that the housing market collapsed is taken to be the cause; but the housing market could collapse for other reasons. People don't just decide that prices aren't high any more. They have to look at supply and demand somewhere in the background. Russ: We did have people holding second and third homes who didn't have the income and capability of repaying the first one. Guest: Sure. Standards were relaxed. But then you have to look on the supply side, the lending side. The people who were lending to these people had the information. Russ: Yes, they knew it. I don't think that they were fooled. They were not overly optimistic about the value of those loans. They were willing to do that because they could sell them. Guest: The puzzle is why they were able to sell them.
24:17Russ: Correct. Now my claim is the people who bought them did it with largely borrowed money. Guest: No, that's not true. These were bought by people all over the world. Russ: Correct. Guest: No one borrowed money. Remember now: savings has to equal lending. For everyone that's short bonds, somebody is on the other side. The net amount of leverage in the world is always zero. Russ: That's true. Guest: So you can't tell a story based on leverage. Russ: So what's your story? I have to think that through. It's undeniably true, and I'm not going to argue with that point. So, what's your explanation of why people bought these things? Guest: Well, I have no explanation. Again, I'd say the market crashes because of the big recession. Even a minor depression if you like. Remember that all the people buying these subprime mortgages all over the world, they are the ones making the loans in the end, they were sophisticated investors. Institutions, big banks all over the world. They thought these things were appropriately priced. They might have been at that time, but they weren't ex post. Russ: So you are not going to allow me to make the claim that the incentives they faced to worry about how appropriately priced were distorted. Guest: The incentives to make money are always there. The question is whether the market lets you make money. So, these people that wanted to securitize all these mortgages, they could have failed at any time in the process; and they would have failed big time because in order to do these things, you have to initially finance them yourself. So when the investment bankers were bringing out the securitized mortgages and other kinds of securitized assets, they initially held them. And they held them afterwards, too. Russ: They held many of them. Guest: Well, initially they held them all, because they are bundling them together; they have to come up with the capital and then they can sell them. So, they could have failed right at that point because the market says: Forget it. We're not paying you par value for these things. Russ: But when they did fail, which they fundamentally did because, at least for them, even though the world wasn't leveraged, they were leveraged, they should have gone out of business. Guest: Right, exactly. Russ: But they did not. Guest: That's awful. That's the worst consequence of this whole episode. Russ: So, my narrative is the anticipation of that distorted their decision-making. Guest: Sure, but that doesn't satisfy what address what goes on on the demand side. Russ: Why? Guest: Because people on the demand side have to buy these things. Russ: Well, the people who were buying them, and selling them, were fundamentally the same people, right? Guest: Okay, so if greed causes me to put out securities that I know are no good, why would I hold them? Russ: Because I can hold them at a very low cost. I have uncertainty; I don't know what's going to happen. There's an upside; there's a downside. Guest: It's really a low cost if you know you are going to get bailed out. Russ: Right. My argument is it dulls your senses. Guest: It does; I agree with you there. Any probability that you are going to be bailed out is going to distort your decision. Russ: So, is your argument then that that was relatively unimportant? Guest: No, no. My argument is it can't explain why people who weren't generating these things and weren't going to be bailed out by us, investors in Norway, whatever--why were they buying? Russ: Well, I'm happy to admit that some people just made a mistake. After the fact. Ex ante they certainly didn't think they were throwing away their money. And a lot of those people making those investments around the world, we bailed them out, too. The European banks got some of the benefits. Guest: Yes, because they were mixed into the same piles that involved our own investment banks. And so they got bailed out in the process. If they were holding credit default swaps (CDSs) that were sold by AIG, they got bailed out. Russ: Although I think Goldman was the number 2 holder of those. The first was--I can't remember; it was a foreign bank, either French or German.
29:19Russ: So, you have publicly said that that was a mistake, those bailouts; we should have let them fail. Guest: It's irrelevant because there is no political regime that will let that happen. Russ: Correct. But let's suppose, let's live in a fantasy world for forty seconds. Suppose on March of 2008, Ben Bernanke and Hank Paulson and the others who got together to talk about the impending bankruptcy of Bear Stearns had just let them go. They would have opened for business Monday morning without enough cash to cover their positions; they would have had to tell their creditors: Sorry; I can't honor the promise I made to you the other day or the other money; and you won't be getting the payment you anticipated. The justification for the intervention was that if we had let that happen there would have been an enormous crisis: credit markets would have frozen up and we would have had a worldwide depression. Guest: I don't know about that last part. That's what we'll never know. The issue is: How long would it take to straighten things out? And I think it's really overrated that it would have taken a large amount of time. So, banks fail all the time, and the FDIC goes in and draws a line in the sand about who is going to get paid and who isn't; stuff is put up for sale and everything goes on. I don't know how long it would take to solve a multiple failure problem. We'll never know. Russ: Well, the Lehman Brother's bankruptcy is still in process. Which is now three years old. This was the argument made at the time--like you, I'm skeptical about it but it has some legitimacy--it's that bankruptcy is complicated enough as it is; when it's a large investment bank with international creditors like Bear, Lehman, it would take a long time. In the meanwhile everybody would be thrown into turmoil. Blah, blah, blah. Do you think there's anything to that? Guest: It's possible. What happened in the Lehman case is it's held up by multiple jurisdictions. So, you have to settle with the British shareholders. Russ: The Japanese, Korean. Guest: Who all have their own set of laws about what happens in a bankruptcy. And that's what I think they've been fighting over for three years. It's pretty clear what assets [?]. Russ: But isn't that an argument for justifying what Bernanke and Paulson did? Guest: I don't know. Because who knows what would have been done if all of them went down. The problem really is that the investment banks weren't subject to the same disposition rules that would face an ordinary commercial bank. They are not subject to the FDIC. And the FDIC can come in and arbitrarily do it. That's what you buy into when you sign up for it. Whereas for the investment banks, they are not really banks; and they are not subject to those rules. The ongoing problem is that you haven't killed their incentive to finance things the way they always have. Russ: Well, I guess my claim is that part of the problem is that we gave a regulatory advantage to triple-A rated stuff, which allowed very large and different amounts of leverage compared to other stuff. That gave an incentive to these folks to find more triple-A. The amount of triple-A is essentially, until recently, there's just not enough of it to go around, if that's the most profitable thing you can do, because that's the thing you can leverage; so they found a way to invent more of it. And that included not just the things we are talking about, but European sovereign debt. Hey, that's safe; let's leverage that, too. Guest: Right. Russ: So, once we said: this is the stuff that you can make scads of money on because you can leverage it and use other people's money. Guest: You are slipping back again, though. Russ: Because? Guest: You are saying that people will buy this stuff even though it isn't triple-A. Russ: Correct. Guest: Why? Russ: Well, that's the puzzle. Is it because they were stupid, ex ante? Guest: We are talking about the world's most sophisticated people who invest. Russ: So is the alternative argument that people just made a mistake? Guest: After the fact, definitely. Whether it was a mistake before the fact, that involves estimating the probabilities of extreme tail events, which, as you know, are very difficult. Russ: So, where does that leave us? Story-telling, of course. Guest: Which is very entertaining but it's not convincing. I don't find it convincing.
34:45Russ: Before I forget, I was going to ask you--I don't want to miss this chance to ask you this: Does your research inform your own personal portfolio decisions? And has it over time? Guest: Oh, sure, always. Russ: Has it changed over time? Guest: Well, I'm not as young as I used to be. Russ: That's part of the theory, too. Guest: Right. So, my portfolio has become somewhat more conservative. I'm also a stockholder in an investment management company, so that part of it is very unconservative. Russ: That's true. Recently--a related question to what we were just talking about before that--the government published the transcripts of the Federal Reserve deliberations in 2006. I don't know if you've looked at that. Guest: No. Russ: Well, one of the most obvious things you learn from reading those transcripts--well, first of all, this is 15 really smart people, very savvy. Their job is to try to figure out what could happen next that could be dangerous. And in 2006, we were on the edge of a collapse in the housing market. And as you argue, maybe just a general problem coming that would be unforeseeable. But what was interesting was that they made the same mistake that I made at the time; and I heard lots of other people much smarter than I am made the same mistake. They said: Well, it's true that there could be a housing price fall; it's been going up for a long time, but the subprimes are essentially only a small part of the whole housing market; housing is only a small part of the overall investment market. So, if this does occur, there's not going to be much of a consequence and we don't have to worry about it. Now, one of the things I think was mistaken, certainly for me as someone not very well versed in finance, and I think most economists are not very well versed in finance, is that we did not understand the role that leverage would play if asset prices fell by a relatively small amount. Do you think that has been a lesson that some people have learned from this crisis? And should we learn that lesson? Guest: Well, leverage will put some people out of business. Russ: Correct. Guest: So, what's the problem? Russ: Well, the problem is that if lots of people go out of business at the same time it allegedly has a multiplier effect--I hate to use that phrase--but that there is some credit market contagion, systemic risk, etc. Guest: That's a word I don't think existed 20 years ago. Russ: Which one? Guest: Systemic. Russ: But let's go back to our mutual friend, Milton. Certainly Milton would argue that the contraction of the money supply at the onset of the Great Depression precipitated by bank failures was something that the Federal Reserve should have paid attention to. Guest: What could they do? Russ: They should have injected liquidity into the system. Guest: Well, but if you have massive free reserves, what is that going to do? Russ: Well, that's a problem. Again, I wish Milton were here. I'm mystified by monetary policy generally, as anyone who has listened to these podcasts knows. Guest: Well, I am too. In the podcasts of this program that I've listened to, I've heard everybody talk about the Fed controlling the interest rates. That's always escaped me how they can do that. Russ: Yes, I'm mystified by it myself. Guest: But I'm in finance, so you've got an excuse. Russ: When I interviewed Milton in 2006 and I asked him why there had been a change in public discussion at least of what the Fed does from changing the money supply to instead manipulating interest rates, his answer was: Well, that's what they say but that's not what they do. They like to say they manipulate interest rates because it makes them feel powerful. All they really do is change the monetary base. And in fact he said, if you look at M2, that's the thing to look at. Guest: That's the thing to look at if you want to know what's happening to business activity. But it's not something you can do anything about.
39:28Russ: I'm with you there. While we're on that subject, do you have any thoughts on why the Fed is paying interest on reserves? Guest: Oh, absolutely. Because they know that if there is an opportunity cost from these massive reserves they've injected into the system, we are going to have a hyperinflation. Russ: So what's the point of injecting the reserves if you are going to keep them in the system? Guest: Exactly. Russ: So what's the answer? Guest: The answer is: this is just posturing. What's actually happened? That debt is now almost fully interest-bearing, all the liquidity that they've injected. So, they've actually made the problem of controlling inflation more difficult. Controlling inflation when they didn't pay any interest focused on the base: cash plus reserves. But now the reserves are interest-bearing, so they play no role in inflation. It all comes to cash, to currency. How do you know? Currency and reserves were completely interchangeable; that's what the Federal Reserve is all about. So I think they've lost it. Now what happened, they went and bought bonds, long-maturing bonds, and issued short-maturing bonds. It's nothing. They didn't do anything. Russ: But they are smart people. Guest: Right. Russ: Ben Bernanke is not a fool. If you could get him alone in a quiet place with nobody else listening and say: Ben, what were you thinking? What do you think he'd say? Guest: I don't know, but I wouldn't believe it. In the sense that at most he could have thought he could twist the yield curve. Lower the long-term bond rate. Now I'm looking at the long-term bond market--it's wide open. Even though they are doing big things, they are not that big relative to the size of the market. Russ: Yes, I am mystified by that as well. I don't have an explanation. Guest: Let me put it differently. So, if I look at the evolution of interest rates, is it credible that in the early 1980s the Fed wanted the short term interest rate to be 13-14%? Russ: No. You are making the argument that it's endogenous; that they can't control it. Guest: Maybe they can tweak it a bit; they can do a lot with inflationary expectations. That will affect interest rates. Turn it around--all international banks think they can control interest rates; and at the same time they agree that international bond markets are open. Inconsistent. Russ: Correct. It reminds of this CNN reporter, credible insight into economic policy. He said: Macroeconomics generally--and fiscal policy, but he could equally as well be talking about Central Bank policy--he said: Politicians who think they can control the economy are like a little kid who is playing a video game; he hasn't put the money in yet and he is watching the arcade game do all its bangs and bells and whistles and noises. Which is an advertisement for the game. And he's pushing the buttons, and he's attributing all the successes on the screen to himself even though he hasn't put the money in yet because he misunderstands the underlying process that generates what he is seeing on the screen. There is some truth to that. Guest: There's a lot of truth to it.
42:51Let's turn to fiscal policy, which you've written some interesting things on lately. You have been very skeptical, as have a few others. And by the way, I should add, before we get into this I should just mention: your view that it's an open question about whether the crisis was averted by these rather remarkable open interventions by the Fed and the Treasury Department in the last few years--it's not a mainstream view. Certainly most economists believe--and I'm with you--but most economists believe that the Fed and the Treasury and the policy makers did a good thing. Guest: That's not taking into account the long term costs. Russ: For sure. And that would be true of most of these interventions. I always find it remarkable that the auto bailout was a success, quote, "because very few people lost their jobs." As if that's the only effect we would ever want to look at. Guest: The long term effects of that are horrendous. Russ: And it's not clear that they saved very many jobs, either. Clearly they changed the incentives. Guest: Not just changed the incentives--they changed the ordering of precedence in contracts. That's something that's really dangerous. Russ: Yes, they abrogated the rule of law. It's very depressing. But on this issue of fiscal stimulus, most economists believe it's a good thing, it works. We are in the minority who suggest that maybe it isn't effective. And recently you wrote a piece suggesting, I would argue, that it's never effective--unless it's well-spent. And I would contrast it with the Keynesian view, which I heard come out of Joe Stiglitz's mouth personally--people can't be what they actually believe--I heard him actually say: It doesn't matter what you spend the money on; it's all stimulus. You are very much on the other side. So, explain why. Guest: When he says it doesn't matter what you spend the money on, I think he thinks there are multiple choices that would all be good. He doesn't think that if you just wash it down the sink, that's good. Russ: Oh, no; he said, when pressed and he was asked: If you ask people to dig ditches and fill them back in, would that stimulate the economy? And he said: Yes; but it's not as good as doing something productive. I can't explain it. It's a mystery to me. Guest: It's a mystery to me, too. Russ: But he's not on the show right now; I wish he were; I'll try to get him down the road. But in your view, talk about what you think the effect of stimulus is and why you are skeptical. Guest: This is a case where you can't be sure. If you look at the empirical evidence, it basically allows you to say anything you want, because the estimates of the effects of stimulus are subject to so much uncertainty. So, I think, though, if I interpreted Christina Romer's stuff properly, or she and her husband's stuff, what it says is that the only thing that clearly gets a pretty good statistical support is permanent [?]intervention [?]. And the other stuff is just [?]. I think that's probably--I'm an empiricist in the end, so that's probably, I don't know. I have my position that I think it's a waste of money, because it will all be wasted. Eventually, you have to finance it. You have to finance it now, which means eventually you have to pay back, future generations have to pay back, for things that are then mostly useless maybe. But the evidence doesn't, like you say. So it's possible for Stiglitz to say one thing; it's possible for you and I to say something entirely different. And neither one can point to the evidence. Russ: I don't view it as a very scientific enterprise. I view it as essentially ideology being wrapped up in scientism, scientific looking, statistical estimation. It seems to me there is too much noise. Guest: I don't agree with what you said when you started; I don't think most economists do think it works. Maybe I'm in the wrong cocoon. Russ: Yes, you need to get out more, Gene, I think. Although I'm in a different cocoon over here on the East Coast; I'm in the only cocoon, I'm at George Mason University and occasionally I'm at Stanford; so we just happen to talk about the three places where there is an overwhelming majority that is skeptical; but outside of those three, I think it's pretty much the other way. Guest: Well, Bob Barro.Russ: Lonely voice, in that enclave. Guest: I think with Barro, famous macroeconomist at Harvard, there's a younger guy. Russ: Alesina. Guest: Council of Economic Advisers. Russ: Oh, Mankiw. Guest: He's skeptical, but what he says is: Once you get into politics, you become a Keynesian. The political pressures are enormous. I think that's right. Russ: It's a terrible view of our intellectual opponents, though. It's not very nice. We don't like it when they attribute our views to being friends of business, which I find repugnant. So, it seems embarrassing to suggest that they hold their views because they like being powerful. I think there's some truth to it, but it's not very nice. You want to hold that view? Guest: Hold which view? I don't know. I don't think economists are different from other people. They all like, have their views, excepted [accepted?] by everybody else, no matter what their views are. Russ: We're prone to incentives; there's no doubt about that. Guest: I've had a tough time for a long time because I believe in efficient markets. Russ: Get a lot of flack.
49:13Russ: Let's go back to finance for a minute. I will put a link up to your recent article on stimulus where you make a theoretical argument against stimulus. Guest: There's no data, right. Russ: And I think basically--it's interesting how the Chicago school has been pushing this--you are using what I would call accounting identities. The money has got to come from somewhere. I expressed it as the resources have to come from somewhere. Guest: That's the right way to say it, actually. Russ: And so I don't understand where the free lunch comes from. Guest: There is no free lunch. Russ: But the counterpoint is that there is a free lunch because there are all these resources laying around. And then it's a question--Milton said this also--how much of the stimulus goes towards the unused, so-called-- Guest: But that's the problem of implementation, which is horrendous. The same problem in regulation: implementation, which is always the killer. Russ: But let's go back to finance. There's been a big trend in recent years towards what's called behavioral finance. What's your assessment of that? Guest: I think the behavioral people are very good at describing microeconomic behavior--the behavior of individuals--that doesn't seem quite rational. I think they are very good at that. The jump from there to markets is much more shaky. Russ: Explain. Guest: There are two types of behavioral economists. There are guys like my friend and colleague Richard Thaler, who are solidly based in psychology, reasoned economics but he's become a psychologist, basically, and he is coming from the research in psychology. Now there are other finance people who are basically what I call anomaly chasers. What they are doing is scouring the data for things that look like market inefficiency, and they classify that as behavioral finance. But to me it's just data judging [?]. Russ: They don't tell you about the times they can't find the anomaly. Guest: Exactly. In all economics research, there is a multiple comparisons problem that never gets stated. Russ: A multiple what? Guest: The fact that the data have been used by so many other people and the people using it now use it in so many different ways that they don't report, that you have no real statistical basis to evaluate and come to a conclusion. Russ: My view is you should video your keyboard so we can see your keystrokes and then we can see what didn't come out. The dishes that didn't come out of the kitchen because you didn't like the way they tasted. Guest: Right. I've had people say to me that the people who do this anomaly stuff, when they come and give a paper and I'll say, when you do this, that, or the other thing, and they'll say Yes. And I'll say, why don't you report it? And they'll say it wasn't interesting. Russ: Not publishable, either. Guest: Well, that's the problem, that there's a counting process [?] and a publication process as well. You do this, that, and the other thing and I'll say, yes, why don't you report it? And they say it wasn't interesting. Russ: It wasn't interesting. Not publishable, either. Guest: Well, that's the problem, there's a publishing process and a culling process as well. This stuff makes it through.
52:37Russ: So, we started off this conversation talking about efficient markets, and we haven't talked about a zillion other things that you've studied that are important in the field of finance. One question I'd like to hear you talk about is the issue of a non-specialist. Let's say I'm just a smart, everyday person and I want to be educated out in the world. What are the lessons for me that finance has learned that are important? There are obviously of findings that have stood up, findings that have had to be modified over the last 50 years that has become more empirical that an educated person should be able to understand and use? Guest: I'm obviously going to be biased. I think all of our stuff on efficient markets would qualify. I think there is a lot of stuff in the corporate area, corporate governance and all of that, a huge field--that has penetrated to the practical level. The Black-Scholes option pricing paper in view is the most important economics paper of the century. Russ: Why? Guest: Because every academic, every economist whether he went into finance or not, read that paper. And it created an industry. In the applied financial domain. What else can claim that? So, I think we've learned a lot about risk and return. Some of it is intuitive. But there is a lot of stuff on which stocks are more or less risky. A lot of stuff on international markets. Now, what should an ordinary, intelligent person know? That's an interesting question. Let me turn it over. What should an ordinary, intelligent person know about pricing? [More to come, 54:55]

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Source: http://www.econtalk.org/archives/2012/01/fama_on_finance.html

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Monday, January 30, 2012

Tigers DH Victor Martinez has knee surgery

updated 12:47 p.m. ET Jan. 30, 2012

DETROIT - Tigers star Victor Martinez is now recovering from surgery on his left knee to repair an injury that is expected to keep him out of the 2012 lineup.

The team announced Monday that Martinez had microfracture surgery on Friday. He is projected to have ACL reconstruction surgery on the same knee in six to eight weeks.

Detroit signed Prince Fielder last week to make up for the loss of Martinez, who tore his left ACL during offseason conditioning.

Martinez hit .330 with 103 RBIs in 2011, helping the Tigers win the division in his first season with them. He signed a $50 million, four-year contract before last season.

Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Source: http://nbcsports.msnbc.com/id/46191978/ns/sports-baseball/

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Sunday, January 29, 2012

Hardest Shot App Measures Slapshot Speeds: Decides If You're NHL Material [Apps]

Using the iPhone's microphone, the NHL's new Hardest Shot app can actually measure the speed of your slapshot and your NHL potential. With the right setup of course. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/eha4nZSHcP0/hardest-shot-app-measures-slapshot-speeds-decides-if-youre-nhl-material

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Finance chiefs reassure CEOs over European crisis (AP)

DAVOS, Switzerland ? Leading finance chiefs sought to reassure anxious global business leaders on Friday that Europe is on track to solve its crippling debt crisis before it drags the world's economies down. Europe's top banker said investors, burned after trusting the region's governments too much, now trust them too little.

The finance chiefs said the picture in Europe has changed over the past two months as the European Central Bank has loaned billions of euros to fragile banks, indebted countries have pushed through convincing reforms and EU leaders have come near to building a closer fiscal union that would make their common currency stronger.

Several also signaled Friday that Greece is close to clinching a crucial debt-reduction deal with private bondholders ? a key element in Europe's efforts to stem a two-year debt crisis that is causing ripples around the globe. The crisis is a central topic at the World Economic Forum, a gathering of government and business leaders at the Swiss ski resort of Davos.

"They're making progress on reforms, they're changing the institutions of Europe to put better discipline on fiscal policy," said U.S. Treasury Secretary Timothy Geithner. "You have three new governments doing some very tough things. You have an ECB doing what central banks have to do. You see them move to try to strengthen the financial sector."

Mario Draghi, head of the European Central Bank, said a combination of actions ? including super-cheap, long-term loans to shaky banks on the continent and a couple of interest rate cuts ? have turned the crisis around.

"We have avoided a major credit crunch, a major lending crisis," he said.

Draghi said borrowing rates would remain high "for quite a while" because bond markets are overestimating the risk involved in holding European government debt after years of underestimating it. But he called market pressure "the most potent engine for reform in different governments."

Geithner said the fate of the U.S. economy ? and by extension of the rest of the world ? hinges on Europe's debt crisis, along with potential tensions with Iran. He said the main piece of unfinished business for Europe is building a bigger fund to help troubled economies survive.

But while French Finance Minister Francois Baroin said that fund needs to be increased to calm markets, his German counterpart, Wolfgang Schaeuble, indicated that his government is not prepared to do so. Germany, as Europe's biggest economy, would face the biggest bill.

"We must not give the wrong incentives," Schaeuble said. "You can make any figure. It will not work if the real problems will not be solved."

Both, together with Spanish Economy Minister Luis de Guindos Jurado and European Monetary Affairs Commissioner Olli Rehn, agreed that the idea of issuing "eurobonds" backed jointly by all eurozone governments is a non-starter for now. They didn't rule out the possibility that such bonds could be introduced once confidence in Europe's public finances is restored, with Guindos calling that a "final target."

Schaeuble said eurobonds would provide bad incentives by allowing debt-ridden countries to "spend money you don't have on the bill of others."

Many economists have said eurobonds are needed to solve the crisis as they could reduce the borrowing costs of heavily indebted countries by pooling them with bonds of stronger economies like Germany's.

European leaders have been especially concerned about Greece, whose borrowing costs are so high that it needs a second European bailout just to pay its interest, but the finance chiefs signaled Friday that a deal is at hand.

Greece has been negotiating with the a group representing banks and other lenders in the hopes that they will forgive half of Greece's debt in exchange for Greek assurances that it will pay back the other half without defaulting on its loans. The deal would also let Greece repay over a longer period at a lower interest rate ? negotiators have been trying to agree on what that rate will be.

Schaeuble said he is "quite optimistic" about a deal, while Rehn said he hopes a deal can be reached "if not today, maybe by the weekend."

Agreement between Greece and its creditors is needed before Europe and the International Monetary Fund agree to a second multibillion-euro bailout package.

At the heart of the problem is that the 17 countries that use the euro use a single currency but have different fiscal policies. That changes the nature of their debt, said Adair Turner, chairman of Britain's banking regulator the Financial Services Authority.

"That debt is more equivalent to the State of California debt than the U.S. federal debt," he said.

That's why all but one of the 27 EU countries ? the United Kingdom has refused to participate ? are discussing a closer fiscal union. On Monday, leaders meet in Brussels to work out the details of that new compact.

Schaeuble and Baroin noted that even the agreement in principle to forge closer ties has calmed markets since a December summit, as borrowing rates have dropped and stock markets have risen.

"It's amazing," Draghi said. "If you compare today with even five months ago, the euro area is another world."

The crisis threatens more than Europe: the U.N.'s refugee chief warned Friday that it is fueling conflicts around the world. Antonio Guterres told The Associated Press that rising food prices and growing unemployment are hitting those already at the bottom hardest, sparking conflict in places like South Sudan and exacerbating hotspots including Afghanistan, Iraq and Somalia.

_____

Frank Jordans in Davos and David McHugh in Frankfurt, Germany contributed to this story.

Source: http://us.rd.yahoo.com/dailynews/rss/eurobiz/*http%3A//news.yahoo.com/s/ap/20120127/ap_on_bi_ge/eu_davos_forum

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Saturday, January 28, 2012

Google Spent Nearly $2 Billion On 79 Acquisitions In 2011

googleYesterday, Google filed its 10-K with the SEC, revealing the number of acquisitions and money spent on these purchases in the year. As of Q3, Google had spent over $1.4 billion on 55 acquisitions for the year. Google ended 2011 spending $1.9 billion (including cash and stock) on completing 79 acquisitions during the entirety of the year. Some of the bigger purchases included ITA Software, which was purchased for $676 million in cash. As we know Google is spending $12.5 billion on Motorola (which isn't included in 2011's calculations), with a termination fee of $2.5 billion if the deal fails to get regulatory approval. The transaction is currently expected to close in early 2012.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/nFfHsSgOkM0/

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Selig expects expanded playoffs to start this year (AP)

NEW YORK ? Commissioner Bud Selig expects baseball to expand its playoffs this season.

Players and owners have already agreed to add an additional wild-card team in each league, but are still deciding whether it would take effect this year or in 2013. Selig said there are scheduling issues to be worked out ? once they are, the new 10-team format would begin with a one-game playoff.

"I really believe we'll have the wild card for 2012, this year," Selig said Friday night in Chicago at a White Sox fan festival. "Clubs really want it. I don't think I've ever seen an issue that the clubs want more than to have the extra wild card this year."

"We're working on dates right now. That'll all take place. It looks to me like we'll have it because I've told everybody we have to have it. It'll be exciting. One-game playoff, it will start the playoffs in a very exciting manner," he said.

A little more than two months before opening day, Major League Baseball hoped to put an end to uncertainty.

Add a bat or an arm to compete for that extra wild card? No telling whether that makes any sense.

"That's the last thing on my mind," Cleveland Indians manager Manny Acta said this week. "I'm trying to win my division and I can't be concerned about that stuff. But the more the merrier.

"It gives us and everybody else a better chance to make the playoffs. But it's not on my mind because you don't build a system or build a team counting on the commissioner is going to change the playoff format," he said.

MLB and the players' association have reached a consensus that ties for division titles will be broken on the field under the new playoff format, a person familiar with the talks told The Associated Press. The person spoke on condition of anonymity because a deal hadn't been finalized.

Since 1995, head-to-head record has been used to determine first place if both teams are going to the postseason. But with the start of a one-game, winner-take-all wild-card round, the sides agreed that the difference between first place and a wild-card berth is too important to decide with a formula and a tiebreaker game would be played.

Negotiators plan to talk again next week and decide by March 1 on whether the extra round will begin this year.

"I think most clubs at this point no matter who you are are focused on trying to win a division," Detroit Tigers general manager Dave Dombrowski said. "If that doesn't work, then you make your adjustments."

Under the new format, whenever it begins, the non-division winners in each league with the two-best records will be the wild-cards, meaning a third-place team could for the first time win the World Series.

Being able to finish third and still go to the postseason could create more of an opportunity in the AL East for teams other than the rich New York Yankees and Boston Red Sox, or in the AL West, where the two-time champion Texas Rangers and Los Angeles Angels have spent big bucks to improve.

In the AL Central, Kansas City general manager Dayton Moore watched Dombrowski add Prince Fielder to his already formidable batting order this week.

"We're focused on putting the best team on the field we can to compete to win the Central. That's the first goal," Moore said. "If that appears to be unattainable, we'll evaluate what we need to do to improve the team to continue to strive for that goal. If it becomes apparent that's not going to happen, you begin to focus on the wild card. You want to get in the playoffs any way you can and take your chances there."

___

AP Sports Writers Rick Gano and Tom Withers contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/sports/*http%3A//news.yahoo.com/s/ap/20120128/ap_on_sp_ba_ne/bbo_expanded_playoffs

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Friday, January 27, 2012

The GOP debate: 7 takeaways (Politico)

JACKSONVILLE , Fla ? This was Newt Gingrich?s last chance to shine on the big stage before Tuesday. It did not go as hoped.

Gingrich and Mitt Romney were supposed to be the main attractions, but Rick Santorum and Ron Paul won notice at the 19th GOP debate, hosted by CNN at the University of North Florida in Jacksonville.

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Below are POLITICO?s seven takeaways:

1) This was the ?Trading Places? debate

For a 120 minutes, Mitt Romney and Newt Gingrich essentially traded roles ? Romney, often meek and shrill-sounding as he defended himself this cycle, became the aggressor, and Gingrich, who?s played the debate hall crowd like a musical instrument in the past, seemed to shrink from the attacks.

Romney came with balled-up fists to the debate stage, and swung hard at Gingrich during the first few questions ? in the exact fashion that the former House Speaker has typically gone at the front-runner.

It worked. Romney had the thing that has eluded him most this cycle ? a ?moment.?

The former Massachusetts governor, apparently having gotten the message that Florida?s outcome could be political life or death for him, slammed Gingrich hard for a now-pulled radio ad in which he described Romney as ?anti-immigrant.? A newly-confident Romney called the charge ?repulsive? and even demanded an apology.

The crowd, in its first roar of the night, loved it ? and Romney was off and running.

Even if there were moments where Romney could have hit Gingrich even harder ? he left the former House Speaker?s support for the individual health care mandate untouched, for instance ? he still gave the most confident answer he?s given to date on being proud of his successes, sounding something close to comfortable, for the first time, discussing his wealth.

Nevertheless, he made mistakes ? saying ?I have a trustee? and declaring he?s never voted for a Democrat if a Republican was also on the ballot were among them, neither of which were necessary to say or helpful to his cause. Two other fumbles: His ?doubting? that a negative ad against Gingrich is being aired by his campaign (it is) and his answer on taxes, which got very in the weeds about his money manager.

But it?s the first half-hour of almost every GOP debate that?s set the tone for the rest ? so the debate counts as a victory for Romney, who needed to keep the momentum from moving away from him again.

2) Whither Gingrich?

It was Gingrich who needed to recapture his momentum and he simply couldn?t do it.

For someone who has made performances in debates central to his candidacy, this was an unusual night.

The former House Speaker, appealingly pugnacious to GOP voters in past debates, simply seemed worn out and off point. Gone was the brawler who could whip up the crowd. And it?s not quite clear where he went.

He never raised any of the well-worn phrases he?s used to define Mitt Romney on the stump ? ?Massachusetts moderate? comes to mind. He also bypassed an opportunity to hit Romney over his Massachusetts health-care plan.

Gingrich?s pushback against Romney over the immigration issue simply failed to connect. He initially tried to avoid repeating his criticisms of Romney?s now-closed Swiss bank account on the debate stage ? something he?s hit him for on the trail in the last few days ? and attempted to retreat toward defending the entire GOP field from the mainstream media?s divisive questions.

Source: http://us.rd.yahoo.com/dailynews/rss/politics/*http%3A//us.rd.yahoo.com/dailynews/external/politico_rss/rss_politico_mostpop/http___www_politico_com_news_stories0112_72066_html/44323135/SIG=11m9iqcms/*http%3A//www.politico.com/news/stories/0112/72066.html

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Jan Brewer, President Obama Trade Barbs on Tarmac


Arizona Gov. Jan Brewer received an earful from President Obama when she met him on an airport tarmac outside Phoenix yesterday - and responded in kind.

The Democratic chief executive and Republican governor could be seen engaged in an intense conversation right at the base of Air Force One's steps.

Both could be seen smiling, but speaking forecefully at the same time. At one point, Jan Brewer pointed a finger directly in Barack Obama's face. Why?

Asked later what the conversation was about, Brewer, who recently published Scorpions for Breakfast, said, "He was a little disturbed about my book."

Something of a memoir of her years growing up, Scorpions defends her signing of Arizona's controversial law cracking down on undocumented immigrants.

Obama, who opposes that law, was objecting to Brewer's description of a meeting they had at the White House in June 2010. Bad blood has boiled since.

Brewer described Obama as lecturing her like "a little kid in a classroom, if you will, and he was this wise professor ... I felt minimized to say the least."

The Governor also said that later that year, Obama blew her off when he was in town to deliver the commencement address at Arizona State University.

On the tarmac Wednesday, Brewer handed Obama an envelope with a handwritten invitation to meet her for lunch and to join her for a visit to the border.

"I said to him, you know, I have always respected the office of the president and that the book is what the book is," she told reporters Wednesday.

She said Obama was upset that she wrote he was not cordial: "I said that I was sorry he felt that way. Anyway, we're glad he's here, and we'll regroup."

The President is visiting the Grand Canyon State to push for initiatives laid out in his State of the Union address, which began his reelection bid in earnest.

Obama in 2012?

Source: http://www.thehollywoodgossip.com/2012/01/jan-brewer-president-obama-trade-barbs-on-tarmac/

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Thursday, January 26, 2012

Nations try to oust Syria from UNESCO rights panel (AP)

PARIS ? A group of UNESCO member states is trying to remove Syria from a committee with a human rights mandate, a panel it quietly rejoined despite its deadly crackdown on protesters.

U.N. Watch, a Geneva-based NGO, diplomats and others said Wednesday that a growing group of countries ? western and Arab ? want to unseat Syria from the Committee on Conventions and Recommendations. The committee deals with multiple issues, but has a strong human rights component.

Syria was named to the committee in November by the Arab group at UNESCO. Now, a number of countries, from the United States and Britain to Qatar and Kuwait, are mounting a campaign to remove Syria from the committee by putting the issue on the agenda of the next executive board. The board meets from Feb. 27 until March 10.

The U.S. ambassador to UNESCO, David Killion, said he "strongly objects" to the reappointment in November of Syria on the committee.

"We should not allow the Syrian regime to stand as a judge of other countries' human rights record while it systematically violates the human rights of its citizens," according to a statement by Killion.

"The Syrian regime's actions are an affront to the dignity and human rights of the Syrian people, and it is not fit to sit on this body."

About 5,400 Syrians have been killed in an uprising that began in March by protesters seeking to topple the regime of President Bashar Assad. U.N. Secretary-General Ban Ki-moon has condemned Syria for human rights abuses.

"Stop killing your people," Ban said in a keynote address to a Jan. 16 conference in Beirut on democracy in the Arab world.

U.N. Watch, the NGO which is affiliated with the American Jewish Committee, made available a December letter to the executive board chairman, signed by 14 nations, advising of the need to act.

The number of signatories has nearly doubled since, according to one diplomat close to negotiations on the issue. The diplomat asked not to be named because of the delicacy of the topic.

An explanatory memo attached to the letter evoked the need for "concerted action to address the egregious human rights situation in Syria."

As a member of the Committee on Conventions and Recommendations, "Syria participates in the examination of cases involving alleged human rights violations ...," the memo reads. "In view of the current situation in Syria, the Executive Board must review the participation of Syria in this aspect of its work."

The signers asked that the question be placed on the agenda of the 58-member board ? of which Syria itself is a member.

It is not at all clear whether a resolution to oust Syria from the committee will be put to the board, or whether something milder, like a condemnation, or something stronger would come forth. Negotiations among nations are in progress.

The diplomat close to the negotiations denied reports that the executive board was asleep at the switch when Syria was reappointed to the committee with a human rights mandate.

The move came as UNESCO's new executive board reorganized. The upcoming board meeting "is the first opportunity that anybody has to confront this issue legally" according to UNESCO's rules, the diplomat said.

Because each regional group can determine who sits on a subcommittee, the decision was "not challengeable."

UNESCO is already trying to overcome the effects of another contentious issue, the withdrawal of U.S. funding after admitting Palestine as its 195th member. The Oct. 31 vote triggered two U.S. laws into action that automatically cut off U.S. funds ? 22 percent of the overall budget.

The law bars U.S. funding of organization that grants membership to territories that are not internationally recognized as states.

Source: http://us.rd.yahoo.com/dailynews/rss/un/*http%3A//news.yahoo.com/s/ap/20120125/ap_on_re_eu/unesco_syria

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hello hello!

thought i would introduce myself, username is silvarak. you may call me silvey for short! I have been roleplaying since i was 14 that's about 5 years! so i have some experience under my belt. ^.=.^ i enjoy almost any kind of roleplay as long as it keeps me interested! like fantasy sci-fi or canon based(like dragonball z or megamind etc etc). also story driven!.
let the pouncing begin!( and i don't mean that in the left field either XD)

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/fNI6dWHzpho/viewtopic.php

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Wednesday, January 25, 2012

Actor James Farentino dies of heart failure at 73 (AP)

LOS ANGELES ? A family spokesman says actor James Farentino, who appeared in dozens of movies and television shows, has died in a Los Angeles hospital. He was 73.

Family spokesman Bob Palmer says Farentino died of heart failure after a long illness at Cedars-Sinai Hospital on Tuesday.

Farentino starred alongside Kirk Douglas and Martin Sheen in a 1980 science fiction film "The Final Countdown."

Farentino also starred opposite Patty Duke in 1969's "Me, Natalie."

He also had recurring roles on "Dynasty," "Melrose Place," "The Bold Ones: The Lawyers" and "ER," playing the estranged father to George Clooney's character.

A four-time divorcee, Farentino's tumultuous personal life made headlines, too.

In March 1994 he pleaded no contest to stalking his ex-girlfriend Tina Sinatra, daughter of Frank Sinatra.

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/ap/20120125/ap_en_ce/us_obit_farentino

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Chipmaker AMD expects lower revenue in weak PC market (Reuters)

(Reuters) ? Advanced Micro Devices Inc (AMD.N) forecast lower quarterly revenue as a shortage of hard drives and a shaky economy hurt PC makers, sending its shares lower in after-hours trading.

The PC chipmaker's fourth-quarter adjusted earnings beat expectations but revenue for the quarter just ended and revenue projections for the current quarter came in a bit below many analysts' expectations.

Like larger rival Intel Corp (INTC.O), AMD has been wrestling with slow demand for chips as consumers increasingly buy Apple Inc's (AAPL.O) iPad instead of laptops.

Also hurting sales of processors, PC manufacturers have been struggling to obtain enough hard drives to meet production targets after flooding last year ruined factories and sensitive machinery in Thailand, the world's No. 2 exporter of the components.

Intel beat scaled-back quarterly earnings expectations last week after warning that the hard drive shortage was hurting PC production. It also warned of lower revenue in the current quarter.

AMD depends more on sales of PC processors for its revenue than does Intel, which sells proportionally more chips for servers. The fact that it expects a similar drop in revenue as Intel suggests AMD might have taken some market share.

"AMD's guidance being equivalent to Intel's suggests to us that AMD has picked up roughly 100 to 110 (basis) points of market share in the PC space." said JoAnne Feeney, an analyst at Longbow Research. "That guidance could also mean AMD is picking up more server market share."

Also on Tuesday, programmable chipmaker Altera (ALTR.O) posted quarterly results above analysts' estimates but its weak first-quarter outlook sent shares down 3 percent after the bell.

With PC sales suffering, AMD and Intel have failed to find a foothold in smartphones and tablets, where processors based on ARM Holdings' (ARM.L) power-efficient chip designs are widely used.

Apple became the largest buyer of semiconductors last year, overtaking Samsung Electronics (005930.KS) and Hewlett-Packard Co (HPQ.N) as sales of iPads and iPhones outpaced PCs and other consumer gadgets, according to market research firm Gartner.

Dogged by concerns the PC chipmaker is being left behind in the fast-growing mobile market, shares of AMD have fallen about 13 percent over the past year.

AMD said revenue in the fourth quarter rose 2 percent from the year-ago period, to $1.69 billion.

But it said revenue in the quarter ending in March would fall 8 percent from the previous quarter, plus or minus 3 percentage points, to around $1.504 billion to $1.606 billion.

Analysts on average expected fourth-quarter revenue of $1.716 billion and March-quarter revenue of $1.595 billion, according to Thomson Reuters I/B/E/S.

Non-GAAP earnings in the quarter were $138 million, compared with $106 million in the year-ago period. Non-GAAP earnings per share were 19 cents, compared with 14 cents in the year-ago quarter. Analysts on average expected earnings per share of 16 cents.

Shares of AMD were down 2.6 percent at $6.36 in extended trade after closing up 0.15 percent at $6.53.

(Reporting by Noel Randewich in San Francisco; Editing by Steve Orlofsky and Matthew Lewis)

Source: http://us.rd.yahoo.com/dailynews/rss/economy/*http%3A//news.yahoo.com/s/nm/20120124/bs_nm/us_amd

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Tuesday, January 24, 2012

Diabetes Mystery: Why are Type 1 Cases Surging?

Image: Getty Images

When public health officials fret about the soaring incidence of diabetes in the U.S. and worldwide, they are generally referring to type 2 diabetes. About 90 percent of the nearly 350 million people around the world who have diabetes suffer from the type 2 form of the illness, which mostly starts causing problems in the 40s and 50s and is tied to the stress that extra pounds place on the body?s ability to regulate blood glucose. About 25 million people in the U.S. have type 2 diabetes, and another million have type 1 diabetes, which typically strikes in childhood and can be controlled only with daily doses of insulin.

For reasons that are completely mysterious, however, the incidence of type 1 diabetes has been increasing throughout the globe at rates that range from 3 to 5 percent a year. Although the second trend is less well publicized, it is still deeply troubling, because this form of the illness has the potential to disable or kill people so much earlier in their lives.

No one knows exactly why type 1 diabetes is rising. Solving that mystery?and, if possible, reducing or reversing the trend?has become an urgent problem for public health researchers everywhere. So far they feel they have only one solid clue.

?Increases such as the ones that have been reported cannot be explained by a change in genes in such a short period,? says Giu?seppina Imperatore, who leads a team of epidemiologists in the Division of Diabetes Translation at the U.S. Centers for Disease Control and Prevention. ?So environmental factors are probably major players in this increase.?

A Challenge of Counting
Type 1 and type 2 diabetes share the same underlying defect?an inability to deploy insulin in a manner that keeps blood sugar from rising too high?but they arise out of almost opposite processes. Type 1, which once was known as juvenile diabetes, is an autoimmune disease in which the body attacks its own cells?namely, the beta cells of the pancreas?destroying their ability to make insulin. In type 2, formerly known as adult-onset diabetes, tissues that need insulin to take up glucose (such as the liver, muscles and fat) become resistant to insulin?s presence. The insulin-producing cells respond by going into overdrive, first making more of the hormone than normal and then losing the ability to keep up with the excess glucose in the blood. Some people end up unable to make insulin at all.

The first strong signal that the incidence of type 1 diabetes was on the rise came in 2006, from a World Health Organization project known as DIAMOND (a combination of words in several languages for worldwide diabetes). That survey, which looked at 10 years of records from 112 diabetes research centers in 57 countries, found that type 1 had risen an average of 5.3 percent a year in North America, 4 percent in Asia and 3.2 percent in Europe.

Statistics from Europe?where the single-payer health care systems that care for residents throughout their lives generate rich stores of data?back up that first finding. In 2009 researchers from a second project called EURODIAB compared diabetes incidence across 17 countries and found not only that type 1 was rising?by 3.9 percent a year on average?but also that it was increasing most quickly among children younger than five. By 2020, they predicted, new cases of type 1 diabetes in that age group will nearly double, from 3,600 children to an estimated 7,076 children.

Most assessments of diabetes in the U.S. have been more partial and local. There is one comprehensive national surveillance project, the federally funded SEARCH for Diabetes in Youth study, which published data in 2007. Because that was an initial report, however, researchers could not compare it with earlier years. Still, when looked at against the findings of other studies, it suggests a rising tide. For example, the 2007 study found higher rates of type 1 in the U.S. than did the WHO?s worldwide study of the year before. In addition, the SEARCH study results were sharply higher than regional studies from the 1990s in Alabama, Colorado and Pennsylvania.

Source: http://rss.sciam.com/click.phdo?i=84f9835f942b7c21177a21376e163e1c

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